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O QUE FARIA SE TIVESSE 15 ANOS // COMO COMEÇAR INVESTIR DESDE CEDO?, time: 10:58

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On July 10, 2008, the swastika CJK unicode character appeared at the top of Google s Hot Trends list a tally of the most used search terms in the United States for several hours. It was later reported that the HTML numeric character reference for the symbol had been posted on bwith a request to perform a Google search for the string. A multitude of b visitors followed the order and pushed the symbol to the top of the chart, though Google later removed the result.

Later that year, the private Yahoo. Mail account of Sarah Palin, Republican vice presidential candidate in the 2008 United States presidential election, was hacked by a 4chan user. The hacker posted the account s password on band screenshots from within the account to WikiLeaks. 124 A b user then logged in and changed the password, posting a screenshot of him sending an email to a friend of Palin s informing her of the new password on the b thread. However, he forgot to blank out the password in the screenshot.

125 A multitude of b users attempted to log in with the new password, and the account was automatically locked out by Yahoo. The incident was criticized by some b users, in that most reports on the hack focused on 4chan, rather than Palin s violation of campaign law. One user commented, seriously, b. We could have changed history and failed, epically. 126 The FBI and Secret Service began investigating the incident shortly after its occurrence.

On September 20 it was revealed they were questioning David Kernell, the son of Democratic Tennessee State Representative Mike Kernell. The stock price of Apple Inc. fell significantly in October 2008 after a hoax story was submitted to CNN s user-generated news site iReport. com claiming that company CEO Steve Jobs had suffered a major heart attack. The source of the story was traced back to 4chan. In May 2009, members of the site attacked YouTube, posting pornographic videos on the site.

130 A 4chan member acknowledged being part of the attack, telling BBC News that it was in response to YouTube deleting music. 131 In January 2010, members of the site attacked YouTube again in response to the suspension of YouTube user lukeywes1234 for failing to meet the minimum age requirement of thirteen. 132 The videos uploaded by the user had apparently become popular with 4chan members, who subsequently became angered after the account was suspended and called for a new wave of pornographic videos to be uploaded to YouTube on January 6, 2010.

132 Later the same year, 4chan made numerous disruptive pranks directed at singer Justin Bieber. In September 2010, in retaliation against the Bollywood film industry s hiring of Aiplex Software to launch cyberattacks against The Pirate Bay, Anonymous members, recruited through posts on 4chan boards, subsequently initiated their own attacks, dubbed Operation Payback, targeting the website of the Motion Picture Association of America and the Recording Industry Association of America.

134 135 136 The targeted websites usually went offline for a short period of time due to the attacks, before recovering. The website of the UK law firm ACS Law, which was associated with an anti-piracy client, was affected by the cyber-attack. 137 In retaliation for the initial attacks being called only a minor nuisance, Anonymous launched more attacks, bringing the site down yet again. After coming back up, the front page accidentally revealed a backup file of the entire website, which contained over 300 megabytes of private company emails, which were leaked to several torrents and across several sites on the Internet.

138 It was suggested that the data leak could cost the law firm up to 500,000 in fines for breaching British Data Protection Laws. In January 2011, BBC News reported that the law firm announced they were to stop chasing illegal file-sharers. Head of ACS Law Andrew Crossley in a statement to a court addressed issues which influenced the decision to back down I have ceased my work.

I have been subject to criminal attack. My e-mails have been hacked. I have had death threats and bomb threats. In August 2012, 4chan users attacked a third-party sponsored Mountain Dew campaign, Dub the Dewwhere users were asked to submit and vote on name ideas for a green apple flavor of the drink. Users submitted entries such as DiabeetusFappleseveral variations of Gushing Grannyand Hitler did nothing wrong.

Threats of violence. On October 18, 2006, the Department of Homeland Security warned National Football League officials in Miami, New York City, Atlanta, Seattle, Houston, Oakland, and Cleveland about a possible threat involving the simultaneous use of dirty bombs at stadiums. 142 The threat claimed that the attack would be carried out on October 22, the final day of the Muslim holy month of Ramadan. 143 Both the FBI and the Department of Homeland Security expressed doubt concerning the credibility of the threats, but warned the relevant organizations as a precaution.

The games proceeded as planned but under a higher level of security awareness. 144 The threats came to light in the national media after Jake Brahm admitted to having posted the threats on 4chan and repeating them on other websites approximately 40 times. On September 11, 2007, at 9 11 am Central time, two pipe bombs will be remote-detonated at Pflugerville High School.

Promptly after the blast, I, along with two ther Anonymous, will charge the building, armed with a Bushmaster AR-15, IMI Galil AR, a vintage, government-issue M1. 30 Carbine, and a Benelli M4 semi auto shotgun. The Pflugerville threat 145. Brahm did not expect the message to be taken seriously since he would never take anything posted on 4chan as fact ; 146 an FBI official was quoted as saying the credibility of the threat was beyond ridiculous.

13 As a parody of the incident, 4chan temporarily added Don t mess with football as an additional rule for b. 13 On October 20, 2006, Brahm turned himself in to federal authorities, and was charged with fabricating a fake terrorist threat and taken into custody. 147 On February 28, 2008, he pleaded guilty to the federal charges. On June 5, 2008, he was sentenced to six months in prison, six months house arrest, and ordered to pay 26,750 in restitution.

Around midnight on September 11, 2007, a student posted photographs of mock pipe bombs and another photograph of him holding them while saying he would blow up his high school Pflugerville High School in Pflugerville, Texas at 9 11 am on September 11. 145 Users of 4chan helped to track him down by finding the perpetrator s father s name in the Exif data of a photograph he took, and contacted the police.

149 He was arrested before school began that day. 150 151 152 153 The incident turned out to be a hoax; the weapons were toys and there were no actual bombs. Jarrad Willis, a 20-year-old from Melbourne, Australia was arrested on December 8, 2007, after apparently posting on 4chan that he was going to shoot and kill as many people as I can until which time I am incapacitated or killed by the police.

155 The post, accompanied by an image of another man holding a shotgun, threatened a shopping mall near Beverly Hills. 156 While the investigation was still open, Willis was charged with criminal defamation for a separate incident 157 but died before the case was heard. On February 4, 2009, a posting on the 4chan b board 159 said there would be a school shooting at St Eskils Gymnasium in Eskilstuna, Sweden, leading 1,250 students and 50 teachers to be evacuated.

160 A 21-year-old man was arrested after 4chan provided the police with the IP address of the poster. Police said that the suspect called it off as a joke, and they released him after they found no indication that the threat was serious. On January 21, 2014, an anonymous poster started a thread on b identifying a student named Westley Sullivan who apparently went to the same high school as the poster. The original post included a link to Westley Sullivan s Facebook profile, which has since been taken down, and a screenshot of a post which said if fairview isnt closed tomorrow im going to blow it upreferring to Sullivan s high school, Fairview High School, in Boyd County, Kentucky.

A few anonymous individuals went to Sullivan s Facebook profile and found his address, phone number, school ID number, school schedule and teachers, and other personal information. Information like his teachers and ID number had been posted directly, and the more personal information like his address was found in the EXIF data of some of the pictures posted on his profile.

These individuals then contacted Fairview school officials and the local police department, as well as the FBI. The next day it was learned that police had arrested Sullivan in his home and he had been charged with 2nd degree terroristic threatening, a Class D felony in Kentucky. On June 28, 2018, a man named Eric M. Radulovic was arrested following an indictment by the U.

Department of Justice on one count of transmitting in interstate and foreign commerce a threat to injure the person of another. 165 The indictment alleged that Radulovic posted anonymously to pol the day after the Unite the Right rally, communicating an intention to attack protestors at an upcoming right-wing demonstration, ostensibly to elicit sympathy for the alt-right movement. I m going to bring a Remington 700 and start shooting Alt-right guys. We need sympathy after that landwhale got all the liberals teary eyed, so someone is going to have to make it look like the left is becoming more violent and radicalized.

It s a false flag for sure, but I ll be aiming for the more tanned dark haired muddied jeans in the crowd so real whites won t have to worry, wrote Radulovic, according to the indictment. Arrests for child pornography. On November 29, 2010, Ali Saad, a 19-year-old, was arrested and had his home raided by the FBI for posting child pornography and death threats on 4chan. Ali had first visited 4chan a week before the FBI raid happened.

He admitted to downloading about 25 child pornography images from 4chan. Collin Campbell, a U. Navy Machinist s Mate, was arrested in February 2011 after a fellow seaman found child pornography on his iPhone that he downloaded entirely from 4chan. 167 168 169 170. Ronald Ohlson, 37, was raided in April 2011 at his upstate New York home by the Department of Homeland Security after he obtained child pornography from 4chan. After 4chan reported a 15-year-old boy in California who posted child pornography, the United States Department of Homeland Security raided his home on June 7, 2011, and took all of his electronic items.

On February 17, 2012, Thaddeus McMichael was arrested by the FBI for child pornography charges after posting comments on Facebook claiming that he possessed child pornography. 173 According to the official criminal complaint filed against Thaddeus, he admitted to obtaining child pornography from the b board on 4chan. Celebrity photo leaks.

On August 31, 2014, a large number of private photographs taken by celebrities were posted online due to a compromise of user passwords at iCloud. 175 The images were initially posted on 4chan. 176 As a result of the incident, 4chan announced that it would enforce a Digital Millennium Copyright Act policy, which would allow content owners to remove material that had been shared on the site illegally, and would ban users who repeatedly posted stolen material. In January 2011, Matthew Riskin Bean, a 20-year-old man from New Jersey, was sentenced to 45 days in prison for cyberbullying on 4chan.

Also in August 2014, 4chan was involved in the Gamergate controversy, which began with unsubstantiated allegations about indie game developer Zoë Quinn from an ex-boyfriend, followed by false allegations from anonymous Internet users. 179 The allegations were followed by a harassment campaign against several women in the video game industry, organized by 4chan users, 180 particularly r9k.

181 Discussion regarding Gamergate was banned on 4chan due to alleged rule violations, and Gamergate supporters moved to alternate forums such as 8chan. Incel spree killers. r9k is a board which implements Randall Munroe s ROBOT9000 algorithm, where no exact reposts are permitted. 184 185 The board was initially centered around NEET and hikikomori lifestyles, 186 and is credited as the origin of the greentext rhetorical style. 187 By 2012, personal confession stories of self-loathing, depression, and attempted suicide, began to supersede b -style roleplaying, otakuand video game discussion.

The users of r9k built upon by then popular 4chan memes epic win and fail to group the human population into alphas or stereotypical well-adjusted popular people and betas or stereotypical geek-ish social rejects, self-identifying with the latter. 186 It became a popular gathering place for the controversial online incel community. 189 190 The beta uprising or beta rebellion meme, the idea of taking revenge against women, jocks and others perceived as the cause of incels problems, was popularized on the sub-section.

191 192 It gained more traction on the forum following the Umpqua Community College shooting, where it is believed that the shooter, Chris Harper-Mercer, also warned people not to go to school in the Northwest hours prior to the shooting as users encouraged him. 193 194 The perpetrator of the Toronto van attack referenced 4chan and an incel rebellion in a Facebook post he made prior to the attack while praising self-identified incel Elliot Rodger, the killer behind the 2014 Isla Vista killings.

195 196 He claims to have talked with both Harper-Mercer and Rodger on Reddit and 4chan and believes that he was part of a beta uprisingalso posting a message on 4chan about his intention the day before his attack. Murder in Port Orchard, Washington. According to court documents filed on November 5, 2014, there were images posted to 4chan that appeared to be of a murder victim. The body was discovered in Port Orchard, Washington, after the images were posted. 199 The posts were accompanied by the text Turns out it s way harder to strangle someone to death than it looks on the movies.

A later post said Check the news for Port Orchard, Washington, in a few hours. Her son will be home from school soon. He ll find her, then call the cops. I just wanted to share the pics before they find me. 199 The victim was Amber Lynn Coplin, aged 30. The suspect, 33-year-old David Michael Kalac, surrendered to police in Oregon later the same day; he was charged with second-degree murder involving domestic violence. 200 Kalac was convicted in April 2017 and was sentenced to 82 years in prison the following month.

Bianca Devins murder. On July 14, 2019, 17-year-old Bianca Devins was murdered by 21-year-old Brandon Clark of Utica, New York after the two went to a concert together. 202 The suspect took pictures of the victim s bloodied deceased body and posted it to Discord and his own Instagram page. 203 The photos were widely shared on Instagram and other sites, particularly on 4chan where many users mocked and celebrated her death, saying she deserved it and praising the killer while depicting Devins as a manipulative young woman.

204 205 Devins had developed a small following online and was a 4chan user herself. AT T temporary ban. On July 26, 2009, AT T s DSL branch temporarily blocked access to the img. org domain host of b and r9kwhich was initially believed to be an attempt at Internet censorship, and met with hostility on 4chan s part.

207 208 The next day, AT T issued a statement claiming that the block was put in place after an AT T customer was affected by a DoS attack originating from IP addresses connected to img. organd was an attempt to prevent this attack from disrupting service for the impacted AT T customer, and. our other customers. AT T maintains that the block was not related to the content on 4chan.

4chan s founder Christopher Poole responded with the following 210 211. In the end, this wasn t a sinister act of censorship, but rather a bit of a mistake and a poorly executed, disproportionate response on AT T s part. Whoever pulled the trigger on blackholing the site probably didn t anticipate nor intend the consequences of doing so. We re glad to see this short-lived debacle has prompted renewed interest and debate over net neutrality and Internet censorship two very important issues that don t get nearly enough attention so perhaps this was all just a blessing in disguise.

Major news outlets have reported that the issue may be related to the DDoS-ing of 4chan, and that 4chan users suspected the then-owner of Swedish-based website Anontalk. Verizon temporary ban. On February 4, 2010, 4chan started receiving reports from Verizon Wireless customers that they were having difficulties accessing the site s image boards. After investigating, Poole found out that only the traffic on port 80 to the boards. org domain was affected, leading members to believe that the block was intentional.

Three days later, Verizon Wireless confirmed that 4chan was explicitly blocked. The block was lifted several days later. Telstra ban. On March 20, 2019, Australian telecom company Telstra denied access to millions of Australians to 4chan, 8chan, Zero Hedge and LiveLeak as a reaction to the Christchurch mosque shootings. 65 Trick Questions That Will Stump You In A Funny Way.

What two things can you never eat for breakfast. What word is spelled incorrectly in every single dictionary. What never asks a question but gets answered all the time. What goes up but never ever comes down. A girl fell off a 50-foot ladder but didn t get hurt. She fell off the bottom rung. What starts with e and ends with e but only has one letter in it. How can a girl go 25 days without sleep.

She sleeps at night. You spot a boat full of people but there isn t a single person on board. Everyone on board is married. How do you make the number one disappear. Add the letter G and it s gone. What s greater than God and more evil than the devil. Rich people want it, poor people have it. And if you eat it, you ll die.

A cowboy rode into town on Friday. He stayed in town for three days and rode out on Friday. Friday was the name of his horse. What two keys can t open any door. A monkey and a donkey. What will you actually find at the end of every rainbow. A young boy was rushed to the hospital emergency room, but the ER doctor saw the boy and refused to operate. This boy is my son, the doctor said.

But the doctor wasn t the boy s father. How could this be. The doctor was the boy s mom. What has a face and two hands, but no arms or legs. What can be caught but never thrown. I start out tall, but the longer I stand, the shorter I grow. How many seconds are there in a year. January 2nd, February 2nd, March 2nd, etc. What can run but not walk.

Thanks to me, you can see straight through the wall. They both weigh exactly one pound. How can the pocket of your pants be empty, but still have something in it. When the something is a hole. What has a thumb and four fingers but isn t actually alive. Imagine you re in a room that s filling up with water quickly. There are no windows or doors. Everyone in the world needs it, but they usually give it without taking it.

What can you hold without touching it at all. Take away one letter and I become even. Seven take away the s and it becomes even. I m light as a feather, but iq option quantos anos even the strongest girl can hold me for more than 5 minutes. Two mothers and two daughters went out to eat, everyone ate one slice of pizza, yet only three slices were eaten. How s that possible. The group included a grandmother, her daughter and her daughter s daughter. What 5-letter word becomes shorter when you add two letters to it.

Can you name three consecutive days without using the words Wednesday, Friday, and Sunday. Yesterday, today, and tomorrow. What gets sharper the more you use it. A man was outside taking a walk when it started to rain. The man didn t have an umbrella and he wasn t wearing a hat or a hood. His clothes got soaked, yet not a single hair on his head got wet. The man was bald. What can you make that no one not even you can see. What belongs to you but gets used by everyone else more than you. What occurs once in a minute, twice in a moment, and never in one thousand years.

I m so fragile that if you say my name, you ll break me. If I drink, I die. If I eat, I m fine. What s full of holes but can still hold liquid. I have teeth but can t eat. First you throw away my outside and cook the inside. Then you eat my outside and throw away my inside. Corn on the cob. Because you throw away the husk, cook the corn. Then you eat the kernels, and throw away the cob.

What runs, but never walks. Murmurs, but never talks. Has a bed, but never sleeps. And has a mouth, but never eats. What bird can lift the most weight. What goes up as soon as the rain comes down. The more you take, the more you leave behind. I have all the knowledge you have. But I m so small, you can hold me in your fist.

How much dirt is there in a hole that s 5 feet wide and 5 feet deep. What has three feet but can t walk. If two s company and three s a crowd, what do four and five make. What travels the world while stuck in one spot. Name four days of the week that start with the letter t. Tuesday, Thursday, today, and tomorrow. What has four eyes but can t see. What s as big as an elephant but weighs absolutely nothing. What moves faster heat or cold. Forwards I m heavy but backwards I m not.

Because you can always catch a cold. A girl leaves home and turns left three times, only to return home facing two guys wearing masks. Who are the two guys. The catcher and the umpire. Beth s mother has three daughters. One is called Lara, the other one is Sara. What is the name of the third daughter. What gets bigger and bigger the more you take away from it.

I have one head, one foot, and four legs. We see it once in a year, twice in a week, and never in a day. If I have it, I don t share it. If I share it, I don t have it. What has one eye but can t see anything at all. CBD What it Does, Types of CBD, Side Effects, and Dosage 2020. 70 Abraham Lincoln Quotes on Life, Religion, and Freedom. The Unedited Truth About What You Really Sign Up For When Hiring A Life Coach.

6 Lessons You Learn When You Become An Orphan In Your 20s. Shine Through The Darkness. What Each Zodiac Wishes They Could Change About Their Past. 50 Eleanor Roosevelt Quotes About Life, Success, and Equality. Previous Close 89. 95 x 1200 Ask 90. 24 52 Week Range 62. Volume 7,112,984. Market Cap 160. 758B Beta 5Y Monthly 0.

28 Volume 2,328,190 Avg. 72 PE Ratio TTM 20. 52 Earnings Date Oct 30, 2020 - Nov 03, 2020 Forward Dividend Yield 4. 26 Ex-Dividend Date Oct 14, 2020 1y Target Est 109. Subscribe to Premium to view Fair Value for ABBV. Weekly Stock List. This is among our most important themes for 2020, and stretches across industries. We think companies that raise their dividends consistently at a double-digit rate are delivering three important signals amid all the recent market volatility 1 the company s balance sheet is strong enough to pay a dividend; 2 management is focused on providing shareholder returns; and 3 management is confident enough in the near-term outlook to raise the payout aggressively.

This third factor is especially important as the pandemic upends the nation s recent record of long-term economic growth. Here are 13 stocks that meet our double-digit dividend test and are on the Argus BUY List. 10 Biggest Pharmaceutical Companies in the World in 2020. The pharmaceutical industry is a trillion dollar industry globally, achieving the milestone for the first time in 2014, and the biggest. 2 Biotech Stocks with Jaw-Dropping Growth Potential. Sorrento Therapeutics and Trillium Therapeutics could both be poised for another explosive move higher.

Allergan Aesthetics and Skinbetter Science Announce The DREAM Initiative To Advance Health Equity and Diversity in Aesthetics. In a world dominated by a pandemic, you might wonder how its affecting the 10 biggest pharmaceutical companies in the world in 2020 click to skip ahead and see the top 3 pharma companies. Today Allergan Aesthetics, an AbbVie company NYSE ABBVand Skinbetter Science announced the launch of a new long-term, educational initiative DREAM Driving Racial Equity in Aesthetic Medicine.

The DREAM Initiative is committed to furthering the principles of racial and ethnic diversity, inclusion, respect and understanding in the fields of dermatology and plastic surgery. 2 Companies That Raised Their Dividends This Week. It s more evidence that dividend activity is improving for U. companies after coming under severe pressure earlier in the pandemic. Dividend Aristocrat AbbVie Declares Its Latest Payout; Yield Is 5.

One of the top dividend stocks in the healthcare sector is getting ready to hand out some cash to shareholders yet again. AbbVie NYSE ABBV announced Friday that its board of directors has declared a fresh quarterly dividend of 1. On Friday s closing share price, it would yield just under 5. AbbVie to Present New Data From 18 Abstracts at the International Congress of Parkinson s Disease and Movement Disorders.

AbbVie NYSE ABBV today announced it will present results from several studies, including the DYSCOVER study evaluating the efficacy of DUODOPA levodopa carbidopa intestinal gel on the duration and severity of dyskinesia in patients with advanced Parkinson s disease PDat the 2020 International Congress of Parkinson s Disease and Movement Disorders Virtual Congress, September 12-16.

In total, 18 abstracts will be presented, including an overview of the pivotal Phase 3 study design for the investigational medicine ABBV-951 in patients with advanced PD, several studies evaluating the economic burden of PD, as well new and updated data evaluating AbbVie s neuroscience portfolio and pipeline. Drug Stocks Look Cheap. Here s Why, According to One Analyst. Drug stocks now fetch about 13. 5 times projected 2021 earnings, against a price to earnings ratio of 20.

2 times for the S P 500 index, leaving the pharmaceutical group at a 30 -plus discount to the overall market, writes J. Morgan analyst Chris Schott in a client note. Drug stocks were at parity to the S P 500 P E ratio as recently as 2018. The pharmaceutical group is up about 2 so far this year, against a 7 gain in the S P 500. AbbVie Declares Quarterly Dividend. The board of directors of AbbVie Inc. NYSE ABBV today declared a quarterly cash dividend of 1.

Pharma Stock Roundup AZN PFE s Coronavirus Vaccine Updates FDA Approvals. AstraZeneca AZN halts coronavirus vaccine study. FDA approves Roche RHHBY and Glaxo s GSK medicines. 2 Top Dividend Stocks to Buy in a Stock Market Crash. These two pharma giants are unlikely to cut their dividend payments during the next market correction. Is AbbVie Stock a Buy. As the youngest of the pharma juggernauts, AbbVie NYSE ABBV is an exciting company because of its impressive size and lineup of popular pharmaceutical and biological products.

Since its spinoff from Abbott Laboratories NYSE ABT in 2013, AbbVie has built an attractive portfolio of drugs while exploring promising programs in oncology, immunology, neuroscience, and more. AbbVie is also attractive to investors thanks to its profitability, consistently growing revenues, and a meaty trailing dividend yield of 5. The Zacks Analyst Blog Highlights Alphabet, UnitedHealth, AbbVie, Adobe Systems and Anheuser-Busch.

3 Safe Blue Chip Stocks to Buy as Market Bounces Back After Tech Selloff. There could be more selling ahead and the election might cause turbulence. Nonetheless, long-term investors might want to consider adding a few safe blue chip stocks to their portfolios. Top Stock Reports for Alphabet, UnitedHealth AbbVie. Halftime Report Traders Weigh In On AbbVie, JPMorgan And More. On CNBC s Fast Money Halftime Report, Stephanie Link said she likes AbbVie Inc NYSE ABBV.

The stock trades at 30 discount to its peers, it has a great immunology franchise and it has synergies from the Allergan purchase. With a yield of 5. 2she thinks it s a great quality stock for the long term. Josh Brown owns Barrick Gold Corp NYSE GOLD and he is looking for more opportunities to buy it into the mid- 20s.

He believes the company is going to be very profitable over the next couple of years, given how low energy prices are and how elevated both gold and copper have become. Jon Najarian said he would buy JPMorgan Chase Co. NYSE JPM on dips. Sarat Sethi still likes Lowe s Companies Inc NYSE LOW. He would be a buyer on a pullback. See more from Benzinga Jon Najarian Sees Unusual Activity In AMD and AGNC Investment Corp Fast Money Halftime Report Picks For September 8 McDonald s, Stewart Information And More Steve Grasso Prefers Cyclicals Over Tech Right Now C 2020 Benzinga.

AbbVie Partners With Chinese Biotech for Cancer Candidate. AbbVie ABBV signs a collaboration agreement with China s I-Mab for developing commercializing the latter s lemzoparlimab to address various cancer types. AbbVie Inks Deal To Develop, Sell I-Mab s Cancer Therapy. AbbVie announced that it has signed an exclusive global collaboration agreement with I-Mab to develop and sell the Chinese biotech company s lemzoparlimab drug candidate for the treatment of multiple cancers.

Under the terms of the agreement, AbbVie ABBV will pay I-Mab 180 million in an upfront payment to exclusively license lemzoparlimab, also known as TJC4, along with 20 million in a milestone payment based on the Phase 1 results, for a total of 200 million. I-Mab will be eligible to receive up to 1. 74 billion in success-based milestone payments for lemzoparlimab, of which 840 million are based on clinical development and regulatory approval milestones, with the remainder based on commercial milestones.

Upon commercialization of lemzoparlimab, AbbVie will also pay tiered royalties from low-to-mid teen percentages on global net sales outside of greater China. In addition, the two partners have the potential to expand the collaboration to additional transformative therapies, they said in the joint statement. Nasdaq-listed I-Mab IMAB stock closed 3.

6 higher at 37. 07 on Friday, while AbbVie iq option quantos anos little changed. Lemzoparlimab is one of the main drug candidates among I-Mab s proprietary and innovative pipeline. It is designed to minimize inherent binding to normal red blood cells while preserving its strong anti-tumor activity, a critical attribute in potentially differentiating lemzoparlimab from other antibodies of the same class currently in development, the company said.

Cancer is the second-leading cause of death globally and the need for novel cancer therapies has never been more acute. The addition of I-Mab s novel CD47 programs complements our global clinical strategy in hematology and immuno-oncology, said AbbVie s chief scientific officer Thomas J. We have been impressed with what I-Mab has been able to accomplish in research and clinical development and we look forward to working together to make a meaningful difference in the lives of millions of patients globally.

I-Mab said results of its recent phase 1 clinical trial confirm possible differentiation of lemzoparlimab in drug safety and a more favorable pharmacokinetics profile in cancer patients. Results have shown that lemzoparlimab is well tolerated as a single agent at a dose range of up to 30 mg kg without any priming dose. Full data will be presented at an appropriate scientific iq option quantos anos later this year. AbbVie shares have recovered after hitting a low in March and are now trading 3.

7 higher than at the start of the year on the back of its acquisition of Botox maker Allergan and solid revenues of Humira. Looking ahead, the 111. 38 average analyst price iq option quantos anos indicates another 21 upside potential in the coming 12 months. Before the collaboration announcement, Citigroup analyst Andrew Baum last week raised the stock s price target to 105 from 98 and reiterated a Buy rating.

Baum believes that the underappreciated revenue and or durability upside from the company s marketed agents Skyrizi, Rinvoq and Imbruvica offsets the current risk from the recently announced congressional subpoena on AbbVie s drug pricing practices. Overall, ABBV scores 11 Buy ratings from Wall Street analysts adding up to a bullish Strong Buy consensus.

See Abbvie s stock analysis on TipRanks. Related News Novavax Pops 8 On Covid-19 Vaccine Data; Analyst Says Buy Amid Pullback Medtronic s First-Of-Its Kind Diabetes System For Young Children Approved AstraZeneca Rises On Report Trump Could Fast-Track Covid-19 Vaccine Candidate More recent articles from Smarter Analyst Buffett s Berkshire Cuts Stake In Wells Fargo As Analyst Flips To Buy United Airlines To Boost October Flight Capacity To 40 Cloudflare vs Fastly Which Stock Has More Upside Potential.

US Backs Microsoft s 10B JEDI Cloud Award; Wedbush Says JEDI Game Changer. AbbVie Partners With I-Mab for Cancer Drug. AbbVie NYSE ABBV has signed a collaboration agreement with Chinese clinical-stage biotechnology company I-Mab NASDAQ IMAB for the development and commercialization of lemzoparlimab, a monoclonal antibody in early-stage clinical testing that could be used to treat various cancers. The antibody targets CD47, a protein that is overexpressed on the surface of many types of cancer cells and delivers a don t eat me signal to the body s immune system.

Under the terms of the agreement, AbbVie will pay I-Mab 200 million now and up to 1. 74 billion in milestone payments in the future. AbbVie Inks 2. They are also new holdings in our Dividend Growth Separately Managed Account and in the Dividend Growers Total Return Trust, sponsored by SmartTrust. 9 Billion Cancer Deal With China s I-Mab. Bloomberg -- U. and Chinese drug developer I-Mab agreed to collaborate on a cancer treatment in a deal that could be worth more than 2. The deal gives North Chicago, Illinois-based AbbVie an exclusive global license to develop and sell I-Mab s cancer-fighting drug outside of Greater China, according to a statement on Friday.

drugmaker AbbVie Inc. The drug lemzoparlimab, also known as TJC4, is an antibody discovered by the Shanghai-based company that is used to treat multiple forms of cancer. AbbVie will pay I-Mab 180 million up front as well as 20 million based on recently-released clinical data, according to the statement. I-Mab could also receive as much as 1.

74 billion in milestone payments based on development, regulatory and sales criteria. The Chinese firm will get royalties from future sales of the drug. The partnership also gives AbbVie a right of first negotiation to license further development and sales of two other lemzoparlimab-based antibodies developed by I-Mab. The potential combined value would be at least 1 billion in upfront and milestone payments.

Separately, I-Mab also announced that a consortium led by Hillhouse Capital has agreed to invest 418 million through a private placement. The deal includes an offering of 29. 1 million ordinary shares to the investors at a price equivalent to 33 for each of I-Mab s American depositary shares, according to another statement. The placement will also see the issue of warrants worth an additional 104. 5 million if fully exercised. Singapore sovereign wealth fund GIC Pte participated in the offering as well.

I-Mab jumped as much as 17. 16 each in New York trading on Friday, while AbbVie rose as much as 1. I-Mab, which raised 114 million in a U. initial public offering in January, had been seeking a partner to jointly develop and sell lemzoparlimab in the world s biggest economy, Bloomberg News first reported in April. The therapy targets a do-not-eat-me signal that allows cancer cells to avoid being targeted by the patient s own immune system, according to I-Mab s website. The drug blocks the signal, allowing the immune system to engulf and eradicate the malignant cells.

I-Mab s deal with AbbVie is the latest large transaction in one of the hottest areas of pharmaceutical research cancer treatments that harness the immune system to fight tumors. Earlier this year, Gilead Sciences Inc. completed the acquisition of immuno-oncology firm Forty Seven Inc. In June, AbbVie agreed a cancer research and development pact with Danish biotechnology company Genmab A S that may generate payments of more than 3 billion. Jefferies LLC is the lead placement agent on I-Mab s private placement, and China Renaissance Holdings Ltd.

participated as a financial adviser. Adds share prices in sixth paragraph. For more articles like this, please visit us at bloomberg. comSubscribe now to iq option quantos anos ahead with the most trusted business news source. 2020 Bloomberg L.

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